Anti Inflammatory Eating Patterns Designed for Real Patients
Level 3, Clinical application
In brief
Anti inflammatory eating patterns, most clearly the Mediterranean pattern, lower inflammatory markers in trials and are associated with lower chronic disease risk. The principles are simple: vegetables, fruit, legumes, whole grains, nuts, seeds, olive and other unsaturated oils and fish, with less ultra processed food, refined carbohydrate, processed meat and alcohol. Designing them for real patients means adapting to budget, time, cooking skills, family and cuisine, and avoiding unfounded restrictions such as universal avoidance of nightshades or dairy.
“Anti inflammatory diet” is one of the most searched nutrition phrases online. It is attached to everything from turmeric lattes to elimination protocols that ban dozens of foods. Beneath the marketing lies a genuine and useful idea: some dietary patterns consistently lower markers of inflammation and are associated with lower rates of the diseases in which inflammation plays a part. This article sets out what those patterns share and how to make them work for patients with real budgets, schedules and families.
What the evidence shows
In the PREDIMED trial, Mediterranean diets supplemented with olive oil or nuts reduced several inflammatory markers compared with a low fat control diet, alongside the reduction in cardiovascular events. Other trials of Mediterranean style and similar patterns have shown reductions in CRP and interleukin 6. Observational research using dietary inflammatory scores has linked more pro inflammatory diets, rich in refined carbohydrates, processed meats and sugary foods, with higher rates of cardiovascular disease, some cancers and depression, although such associations have the usual limitations of observational data.
Much of the anti inflammatory effect of these patterns likely comes from their combined effects on weight, visceral fat, glucose control, the microbiome and the replacement of ultra processed foods, rather than from any single ingredient.
The shared principles
| Emphasise | Reduce |
|---|---|
| Vegetables and fruit of many colours | Ultra processed foods |
| Legumes: beans, lentils, chickpeas, peas | Refined grains and added sugars |
| Whole grains and traditional grains such as millets, oats and barley | Sugar sweetened drinks |
| Nuts and seeds | Processed and heavily charred meats |
| Olive oil and other unsaturated oils | Deep fried foods and industrial trans fats |
| Fish, especially oily fish | Excess alcohol |
| Herbs and spices | |
| Fermented foods such as yoghurt and fermented vegetables |
Myths worth addressing
- Nightshades cause inflammation. Tomatoes, peppers, potatoes and aubergines are commonly blamed, but there is no good evidence that they cause inflammation in people generally. Individual intolerance is possible and can be tested through structured elimination.
- Dairy is inflammatory. Meta analyses of trials have not shown that dairy increases inflammatory markers in most people, and fermented dairy is associated with favourable outcomes. People with allergy or intolerance are exceptions.
- Grains are inflammatory. Whole grains are associated with lower inflammation and chronic disease risk. Refined grains are a different matter. Coeliac disease and wheat allergy are specific exceptions.
- Supplements can replace diet. Turmeric, fish oil and other supplements have at most modest effects compared with a whole dietary pattern.
Designing for real life
Budget
- Dried or tinned legumes are among the cheapest sources of protein and fibre.
- Frozen vegetables and fruit are nutritious and reduce waste.
- Tinned oily fish such as sardines and mackerel costs less than fresh.
- Seasonal and local produce, oats, eggs and whole grains bought in bulk are affordable staples.
- Olive oil can be expensive in some countries; other unsaturated oils such as rapeseed, groundnut or mustard oil, depending on local availability, are suitable.
Time
- Batch cook legumes, grains and sauces at weekends.
- Use simple templates: a grain, a legume or protein, 2 vegetables, a sauce.
- Keep ready to eat options: pre washed salad, tinned beans, frozen vegetables, nuts, yoghurt, fruit.
Family
Changes are easier when the whole household eats similar food. Adding vegetables and legumes to familiar dishes is often more acceptable than introducing unfamiliar meals.
Cuisine
The principles fit most food cultures.
| Cuisine | Anti inflammatory building blocks |
|---|---|
| South Asian | Dal, chana, rajma, vegetable sabzis, curd, whole wheat or millet rotis, spices; less fried food and sugar |
| East Asian | Tofu, fish, leafy greens, seaweed in moderation, brown rice, fermented foods; watch salt |
| Mediterranean and Middle Eastern | Olive oil, legumes, vegetables, whole grains, fish, yoghurt, herbs |
| West African | Beans, leafy green soups, okra, groundnuts, fish, whole grains such as millet and sorghum; less palm oil and fried food |
| Latin American | Beans, maize tortillas, avocado, vegetables, salsas, fish; fewer sugary drinks and fried foods |
| Northern European | Oats, rye, root vegetables, berries, cabbages, oily fish, rapeseed oil |
A starter plan
- Week 1: replace sugary drinks with water or unsweetened drinks.
- Week 2: add a portion of legumes most days.
- Week 3: fill half the plate with vegetables at one main meal, then both.
- Week 4: swap one refined grain for a whole or traditional grain.
- Week 5: include oily fish twice a week, or nuts and seeds daily for vegetarians.
- Week 6: reduce processed meat and ultra processed snacks.
Measuring progress
For patients with raised inflammatory markers, rechecking hsCRP after several months of change, along with weight, waist, lipids and glucose markers, shows the effect. For many, improvements in energy, digestion and sense of wellbeing are as motivating as numbers.
An illustrative case
A 52 year old single mother working 2 jobs has rheumatoid arthritis, a raised CRP despite medication, and a diet of instant noodles, white bread and fried takeaway food. She has little money and less time. Her plan uses a weekly batch cook of a large pot of lentil and vegetable stew from dried lentils, frozen vegetables and tinned tomatoes; oats with frozen berries for breakfast; tinned sardines on whole grain toast twice a week; and water in place of fizzy drinks. Her rheumatologist continues her treatment. 3 months later she is eating more vegetables and legumes than ever, spending no more on food, and her CRP has fallen alongside improved disease control. Nothing she eats is expensive or exotic.
Principles, not prohibitions
The most effective anti inflammatory diet is not a list of banned foods or a shelf of supplements. It is a pattern built from affordable, familiar foods, shaped to the patient’s life and sustained over time.
Questions about anti inflammatory eating
What is an anti inflammatory diet?
Do nightshades cause inflammation?
Can anti inflammatory eating be affordable?
References
- Casas R, Sacanella E, et al. The effects of the Mediterranean diet on biomarkers of vascular wall inflammation and plaque vulnerability in subjects with high risk for cardiovascular disease: a randomized trial. PLoS One. 2014;9(6).
- Shivappa N, Steck SE, Hurley TG, et al. Designing and developing a literature derived, population based dietary inflammatory index. Public Health Nutrition. 2014;17(8).
- Bordoni A, Danesi F, Dardevet D, et al. Dairy products and inflammation: a review of the clinical evidence. Critical Reviews in Food Science and Nutrition. 2017;57(12).
- Schwingshackl L, Hoffmann G. Mediterranean dietary pattern, inflammation and endothelial function: a systematic review and meta analysis of intervention trials. Nutrition, Metabolism and Cardiovascular Diseases. 2014;24(9).
- Estruch R, Ros E, et al. Primary prevention of cardiovascular disease with a Mediterranean diet supplemented with extra virgin olive oil or nuts. New England Journal of Medicine. 2018;378(25).
Continue your learning
Making healthy eating practical
Designing practical eating plans that patients can sustain is at the heart of IIFM’s 6 month Functional Medicine and Clinical Nutrition program, especially its “Cardiometabolic Diet Therapy” and “Applied Clinical Nutrition” modules.
This article is for the education of healthcare professionals. It is not a substitute for individual medical advice, diagnosis or treatment, and does not change any practitioner’s scope of practice. Regulation and guidelines differ between countries.

