Why Healthcare Needs an Integrated Approach

Level 1, Fundamentals

In brief

Patients commonly combine conventional treatment with supplements, dietary practices, allied health and traditional or complementary care, often without any single practitioner seeing all of it. An integrated approach makes that care visible, so interactions, product risks, duplication and delayed diagnosis can be caught, and so that each approach can be weighed by evidence and coordinated into one plan.

A man in his sixties is admitted with bleeding after a minor fall. He takes warfarin for atrial fibrillation, prescribed by his cardiologist. His family doctor recently started an antibiotic for a chest infection. He has been taking a high dose fish oil capsule his daughter recommended, a ginkgo supplement for his memory and a herbal preparation from a traditional practitioner for his joints. Each decision made sense on its own. Nobody had seen them together.

Scenarios like this are not rare exceptions. They are the predictable result of how modern care is organised: many practitioners, many products, and a patient who is the only person holding all the pieces. This article sets out why that fragmentation matters, what goes wrong when care is not integrated, and what practitioners in any discipline can do about it.

The scale of parallel care

Traditional and complementary medicine is not a niche. The World Health Organization’s global report found its use reported in the great majority of member states, across every region, and many countries have developed national policies to regulate it. Dietary supplement use is widespread in many high income countries, and self directed dietary change, from intermittent fasting to elimination diets, is increasingly common.

Alongside this, research has repeatedly found that many patients do not tell their doctors about supplements or herbal products unless asked directly. The reasons patients give are revealing: the doctor did not ask, they did not think it was relevant, or they expected disapproval. Each of those reasons is within a practitioner’s power to change.

What goes wrong when care is fragmented

Pharmacological interactions

Some of the best documented interactions in clinical pharmacology involve herbal products and foods. St John’s wort induces drug metabolising enzymes and drug transporters, and can reduce the blood levels and effect of medicines including certain oral contraceptives, ciclosporin, warfarin, digoxin and some antiretrovirals; combined with serotonergic antidepressants it may contribute to serotonin toxicity. Grapefruit inhibits intestinal drug metabolism and can raise levels of several medicines. Liquorice taken regularly in significant amounts can raise blood pressure and lower potassium. Products with antiplatelet or anticoagulant effects, alone or in combination, may add to bleeding risk in patients taking anticoagulants, although for many individual products the evidence is limited to case reports and plausible mechanisms.

Absorption and timing

Less dramatic but far more common are absorption interactions. Calcium, iron and some other mineral supplements reduce the absorption of levothyroxine and should be separated from it by several hours. Mineral supplements can also bind some antibiotics. Patients rarely know this unless someone who sees both the prescription and the supplement tells them.

Laboratory interference

High dose biotin, widely sold for hair and nails, can interfere with some immunoassays and produce falsely high or falsely low results, including in some thyroid function and cardiac troponin tests. Regulators have issued warnings about this. A practitioner who does not know the patient is taking biotin may misread a result and change treatment unnecessarily.

Product quality

Regulation of supplements and traditional preparations varies greatly between countries and manufacturers. Analyses have found heavy metals in some traditional Ayurvedic products and undeclared pharmaceutical ingredients in some products sold as herbal or natural, particularly those marketed for weight loss, sexual performance and joint pain. Quality is therefore a clinical question, not only a consumer one.

Delayed diagnosis

When symptoms are being managed in several places at once, warning signs can go unrecognised. Persistent indigestion managed with herbal remedies, weight loss attributed to a new diet, or back pain treated in parallel by several practitioners may each delay investigation of something serious.

Duplication and burden

Fragmented care also wastes time and money. Patients may repeat similar tests with different practitioners, take several products with overlapping ingredients, and follow conflicting advice. The burden of managing it all falls on the patient.

Why integration is the answer, not just more caution

One response to these risks is to advise patients to stop everything that is not prescribed. In practice that rarely works. Patients who feel their choices are dismissed often continue them quietly and stop disclosing them, which is the worst outcome of all. An integrated approach takes a different route: it makes all of a patient’s care visible, evaluates each part honestly, and coordinates what remains.

The evaluation rests on 4 questions. What is the evidence for this approach in this condition? Is it relevant to what is driving this patient’s illness? Is it safe alongside everything else they use? Does it fit their context, preferences and access to care? Answering them often leads to a shorter list of interventions, not a longer one, and to a patient who understands why.

A practical workflow for any practitioner

Integration does not require a new discipline. It requires a few consistent habits.

  1. Ask with examples. “Besides your prescriptions, do you take any vitamins, supplements, herbal teas, traditional remedies or products from a health shop? Do you see anyone else for your health, such as a physiotherapist, chiropractor, acupuncturist, naturopath or a practitioner of a traditional system?” Examples prompt memory.
  2. See the products. Ask patients to bring every product, including packaging. Names on labels reveal ingredients patients cannot remember, and doses that are sometimes surprising.
  3. Place each item on the timeline. When was it started, by whom, and for what? Products started just before new symptoms deserve particular attention.
  4. Screen for the high risk combinations. Anticoagulants, antiplatelet drugs, levothyroxine, immunosuppressants, antiepileptics, antiretrovirals, lithium and other narrow therapeutic range medicines warrant a careful review of every co administered product.
  5. Communicate, do not override. If you are not the prescriber, raise concerns with the prescriber. Explain to the patient why, without alarm.
  6. Write one summary. A single list of everything the patient uses, shared with consent, is one of the most valuable documents in their care.
  7. Review. Agree a date to reassess what is helping, what is not and what can stop.

Consider how this workflow plays out in a composite case.

6 practitioners, one plan

A 52 year old man with chronic low back pain and newly raised blood pressure is seeing his family doctor, a physiotherapist and an acupuncturist. He takes an herbal anti inflammatory product bought online and drinks liquorice tea several times a day for indigestion. He has recently started an antihypertensive.

A dietitian taking a full history lists every product and practitioner. She notices 2 things: he stopped his home exercise programme 3 months ago because of pain, and his liquorice intake began at around the time his blood pressure rose. She explains to him why liquorice matters, suggests an alternative for his indigestion, and writes a short note to his doctor listing everything he takes and asking the doctor to review the herbal product and check his potassium. She contacts the physiotherapist, with his consent, about restarting a graded programme.

At review, his blood pressure has improved, his potassium is normal and he has resumed his exercises. The acupuncture continues because he values it and it poses little risk. His care is not smaller in scope, but it is now one plan.

What each profession brings

Integration is not the job of one profession. Physicians and pharmacists hold the clearest view of medication risk. Dietitians and nutritionists often take the fullest dietary and supplement histories. Health coaches frequently spend the most time with patients and hear about practices others do not. Physiotherapists see how pain and function change over time. Practitioners of traditional systems understand what their own recommendations are intended to do. Each can act as the integrator when they are the one who sees the whole picture, provided they stay within their own scope and share what they find.

The systems perspective

There is a deeper reason integration fits naturally with functional medicine. Functional medicine treats the body as a set of interacting systems, where a change in one affects the others. The care a patient receives is also a system. A supplement changes a medicine’s effect; a diet changes a laboratory result; a physiotherapy programme changes pain, activity, sleep and mood. Treating care as a system is simply applying the same logic one level up.

Questions about integrating care

How common is traditional and complementary medicine use?
The World Health Organization reports its use in the great majority of member states, across every region.
What are the risks of uncoordinated care?
Interactions, poor product quality, delayed diagnosis and duplication of tests and treatment.
Are supplements safe to combine with medicines?
Some are and some are not. Each should be considered for rationale, evidence, safety, interactions and quality.

Sources

  1. World Health Organization. WHO global report on traditional and complementary medicine 2019. Geneva: WHO; 2019.
  2. Kennedy J, Wang CC, Wu CH. Patient disclosure about herb and supplement use among adults in the US. Evidence Based Complementary and Alternative Medicine. 2008;5(4).
  3. Izzo AA, Ernst E. Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs. 2009;69(13).
  4. United States Food and Drug Administration. Biotin (vitamin B7): safety communication, may interfere with lab tests. 2017, updated 2019.
  5. Saper RB, Phillips RS, Sehgal A, et al. Lead, mercury, and arsenic in US and Indian manufactured Ayurvedic medicines sold via the Internet. JAMA. 2008;300(8).
  6. Tucker J, Fischer T, Upjohn L, et al. Unapproved pharmaceutical ingredients included in dietary supplements associated with US Food and Drug Administration warnings. JAMA Network Open. 2018;1(6):e183337.

Continue your learning

Seeing the whole patient, in practice

Integration starts with a history that captures everything a patient uses, and a method that turns it into one plan. The 6 month Functional Medicine and Clinical Nutrition program teaches that history and method, and gives practitioners repeated practice on real cases.

This article is for the education of healthcare professionals. It is not a substitute for individual medical advice, diagnosis or treatment, and does not change any practitioner’s scope of practice. Regulation and guidelines differ between countries.